[Post-transplantation diabetes in kidney transplant: from the diabetologist point of view].

Service d'endocrinologie, diabétologie et métabolisme, CHUV, 1011 Lausanne. Service de néphrologie, CHUV, 1011 Lausanne. Centre de transplantation d'organes (CTO), CHUV, 1011 Lausanne. Service de pharmacie, CHUV, 1011 Lausanne.

Revue medicale suisse. 2020;(697):1200-1205

Abstract

Post-transplantation diabetes (PTDM) exposes to increased morbidity (cardiovascular or infectious complications, early graft dysfunction) and to a risk of premature death. Recognition of risk factors is essential for early and individualized care. The management of a PTDM requires the use of oral antidiabetic treatments (metformin or DPP4 inhibitors) or GLP1 receptor agonists for their favorable effects on weight and kidney that seem ideal in this context. Corticosteroid-induced diabetes or the rare occurrence of diabetic ketoacidosis require insulin therapy. In the long term, the main objective remains to integrate PTDM treatment in a more comprehensive management, targeting the reduction of cardiovascular risk of vulnerable transplant patients.

Methodological quality

Publication Type : Review

Metadata

MeSH terms : Kidney Transplantation